Serious doubts on value of clinical trials

It’s a no brainer that evidence based medicine is a good idea. Who doesn’t want to know that there is is some form of testing going on to find out if your treatment is likely to work? The medical profession, or most of it, confidently asserts that this is the way medicine is done these […]

Tamiflu: evidence-free yet we spent millions on it

Following up on the article in the Mail today about Pharmageddon – a book that  details the way companies hide inconvenient data to the detriment of patients – I was struck by how the Tamiflu saga was a perfect example of what the author Professor David Healy was talking about. It also raises the issue of […]

Drug companies and off label

News item from Pulse that following legal challenge by Novartis about off label prescribing of cheaper Lucentis that there is now talk of doctors not being allowed to prescribe off label if there is a licenced alternative. This has nothing to do with protecting patients and everything to do with protecting profits. Off label prescribing has […]

Drug company sues over off label prescribing

Yesterday the drug company Novartis announced it was taking the NHS to court to protest about  off-label prescribing, that’s when a drug is given to patients even though it doesn’t have a license to treat that particular condition. “It’s unacceptable to put the safety of patients at risk,” said a spokesperson for the company “though widespread use […]

Pharmageddon: how distortion and cover up happens

The most detailed and passionate statement of what has gone wrong with evidence based medicine and how it is damaging patients can be found in a new book called Pharmageddon by psychiatrist and campaigner Professor David Healy  (published by the University of California Press, £27.95).  I wrote a summary of the book with David Healy, […]

Prescribing off label – common and unscientific

Two recent reports have just peered into a murky corner of evidence based medicine and found illegal doings and a distinct lack of evidence Over 11% of the prescriptions handed out in Canada were done off-label, according to a study published yesterday What this means that there weren’t clinical trials backing up their use for that condition. […]

Rattling with pills as you grow older

As you peer into your medical future among the nasties lurking for you will be lots of pills. Fifty percent of people over 65 are on five or more drugs – the medical version of five-a-day – unless of course you have read ‘The 10 Secrets of Healthy Ageing’, my new book written with Patrick […]

Statins: worth it or not when you are healthy?

If any preventative drug use had good evidence supporting it, you’d think cholesterol-lowering statins would. They are given out to around five million healthy people in the UK with the aim of lowering their risk of having a heart attack. For fifteen years or more there have been hundreds of large-scale double-blind, evidence-based-medicine gold-standard trials […]

Alzheimer’s funding boost 1

The announcement last month (March 25th) the Alzheimer’s funding was to be doubled by 2015 is to be welcomed. But what is the money going to be spent on? Two separate developments don’t inspire confidence that it will always be the most safe and effective treatments. The first concerns the latest developments with the drug […]

Yellow Card: parcelling up risk

This was the first posting on on this blog, all the earlier ones are articles.  Following up on my feature in the Mail today  around Professor Gotzsche’s excellent new book about why it is a really bad idea to have a mammogram I’ve been picking up a lot of material around the issue of evidence […]